Enzyme based fuel cells consist of enzymes on the electrodes for carrying out the needed reactions.  The anode enzyme electrooxidizes an anode reductant and the cathode enzyme electroreduces a cathode oxidant.  Hydrogels may be used to conduct a current between the electrodes.  (Heller, US Patent 7,811,689, 10/12/2010)

Recent US Patents

10/12/1010
7,811,689
Biological fuel cell and methods

Heller of Abbott Diabetes Care, California has developed a fuel cell with anode enzyme disposed on the anode and cathode enzyme is disposed on the cathode.  In addition, anode redox hydrogel on the anode to traansmits current between the anode and the anode enzyme and cathode redox hydrogel transmits a current between the cathode and the cathode enzyme. (RDC 1/11/2011)

Recent Journal Articles

2/4/2011
Activity of an Enzyme Immobiized on Polyelectrolytes Multilayers
(52-56)
Polymer Science: Series A 53 #1 (2011)
Malinin et al immobilized α-chymotrypsin on the surface of boron silicate glass microspheres is conducted via the technique of multilayer adsorption of polyelectrolytes.  The enzyme is adsorbed on both positively and negatively charged surfaces and its activity is partially preserved relative to that in solution. The activity of the enzyme depends on the number of polyelectrolyte layers preliminarily adsorbed on glass microspheres and on the charge of the surface. The activity of α-chymotrypsin adsorbed on the negatively charged surface is four times higher than the activity of this enzyme adsorbed on a positively charged surface.  (RDC 2/9/2011)