Functionalization by Click Reactions

Polymers can be functionalized using Click reactions.  (RDC 7/18/2011)

Click Reactions
Functionalization
Polyethylene Functionalization by Click Reactions
Reactions

Recent Journal Articles

Surface functionalization of nanofibrillated cellulose using click-chemistry approach in aqueous media
(1201-1212)
 Cellulose 18 #5 (2011)

Pahimanolis et al of the Aalto School of Chemical Technology, Finland prepared amino functionalized nanofibrillated cellulose (NFC)  using click-chemistry in aqueous reaction conditions.  First, reactive azide groups were introduced on the surface of NFC by the etherification of 1-azido-2,3-epoxypropane in alkaline water/isopropanol-mixture at ambient temperature.  Then the azide groups were reacted with propargyl amine utilizing copper catalyzed azide-alkyne cycloaddition (CuAAC), leading to pH-responsive 1,2,3-triazole-4-methanamine decorated NFC.  (RDC 8/9/2011)

Synthesis of Alkyne-Functionalized Helical Polycarbodiimides and their Ligation to Small Molecules using ‘Click’ and Sonogashira Reactions
(5947–5954)
Macromolecules 44 #15 (2011)

Budhathoki-Uprety and Novak of North Carolina State University, North Carolina, synethesized terminal alkyne side chain functionalized polycarbodiimides. “Alkyne” ligation tools—“click” (copper-catalyzed Huisgen 1,3-dipolar cycloaddition reaction) and Sonogashira couplings—were used to create functional polycarbodiimides in one step postpolymerization modifications.  (RDC 8/2/2011)

Efficient synthesis of zwitterionic sulfobetaine group functional polyurethanes via “click” reaction
(1251–1257)
Journal of Applied Polymer  Science 122 #2 (2011)
Huang and Xu of Donghua University and Wuhan Textile University, China, synthesized a polyurethane material containing zwitterionic sulfobetaine groups  using the copper-catalyzed 1,3-dipolar cycloaddition (azide-alkyne click chemistry).  A standard two-step polyaddition method was used to produce the well-defined polyurethane based on polycarbonatediol (PCDL) with alkyne groups.  These polyurethanes containing alkyne units were then efficiently clicked using 3-((2-azidoethyl)dimethylammonio)propane-1-sulfonate (DMPS-N3).  This facile “click” reaction provides a useful tool for the development of novel functional polyurethanes for biomedical applications.  (RDC 7/13/2011)