Fungicides
Fungicides are chemical compounds or biological organisms used to kill or inhibit fungi or fungal spores. Fungi can cause serious damage in agriculture, resulting in critical losses of yield, quality and profit. Fungicides are used both in agriculture and to fight fungal infections in animals. (Wikipedia, Fungicides, 7/1/2010 )
Recent US Patents
1/4/2011
7,863,465
Antifungal agents
Balkovec et al of Merck Sharp & Dohme, New Jersey and Scynexis, North Carolina, have developed enfumafungin derivatives and pharmaceutically acceptable salts as inhibitors of (1,3)-.beta.-D-glucan synthase. The present compounds and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the present compounds and pharmaceutically acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions. (RDC 7/18/2011)
9/14/2010
7,795,178
Fungicidal active combinations spiroxamine, prothioconazole and tebuconazole
Mauler-Machnik of Bayer, Germany, have developed a fungicide based on a mixture of the three compounds; the fungicidal activity is considerably higher than the sum of the activities of the individual active compounds. (RDC 11/19/2010)
Recent Journal Articles
Electrospun biohybrid materials for plant biocontrol containing chitosan and Trichoderma viride spores
(48-55) Journal of Bioactive and Compatible Polymers 26 #1 (2011)
Abstract
Spasova et al of the Bulgarian Academy of Sciences and Agricultural University, Bulgaria prepared nanofibrous mats containing chitosan and Trichoderma viride spores by electrospinning. . The fungal spores incorporated into the chitosan-containing fibrous mats were viable; the T. viride developed and reproduced normally. The electrospun biohybrid materials inhibited the growth of diverse phytopathogenic strains (Fusarium, Alternaria) when placed at suitable growth conditions. Coating the plant sprouts with the biohybrids by direct electrospinning was easily done. (RDC 2/19/2011)
Molecular weight-dependent antifungal activity and action mode of chitosan against Fulvia fulva (cooke) ciffrri
( 3127–3135)Journal of Applied Polymer Science 119 #6 (2010)
Li et al showed that chitosan in vitro, exhibited strong antifungal activity against F. fulva. Scanning electron microscopy showed that chitosan could induce the hyphal swelling. The surface of hypha which was treated with low Mw (82 KDa) chitosan was smooth, but was rough treated with high Mw