1/7/2010
Morphology of crosslinked hyaluronic acid porous hydrogels
(1040–1049)Journal of Applied Polymer  Science 120 #2 (2011)
Collins and Birkinshaw of University of Limerick, Ireland crosslinked hydrogels, based on hyaluronic acid or hyaluronan (HA) to reduce its degradation rate and freeze dried to produce porous materials suitable for tissue engineering.  Chemical modification increases sponge density and wall thickness of the pores while decreasing the pore size. These materials have an average pore size ranging from 167 to 215 μm, which suggests that they would be a suitable temporary site for cell proliferation.  (RDC 1/10/2011)