Interpenetrating Network Drug Release Systems
Interpenetralting networks can be effective drug release systems. (RDC 1/10/2010)
Recent Journal Articles
1/7/2011
Preparation, properties, and drug release of thermo- and pH-sensitive poly((2-dimethylamino)ethyl methacrylate)/poly(N,N-diethylacrylamide) semi-IPN hydrogels
(1523-1534) Journal of Materials Science 46 #5 (2011)
Zhang et al, China showed that the interior morphology by scanning electron microscopy is an interconnected porous network structures. The semi-IPN hydrogels showed fast swelling and deswelling rates in response to temperature and pH change. These results suggest that the stimuli semi-IPN hydrogel have potential application as intelligent drug carriers. (RDC 1/12/2011)
Synthesis and Characterization of Sodium Alginate-g-2-Hydroxyethyl Methacrylate Interpenetrating Beads for Controlled Release of Acebutolol Hydrochloride
(25-37) Designed Monomers and Polymers 14 #1 (2011)
Yerriswamy et al of Krishnadevaraya University, India prepared the beads by free-radical polymerization. Poly(HEMA)-grafted-sodium alginate beads were produced by solvent evaporation using glutaraldehyde as the cross-linking agent. This resulted in a mean particle size of 100 μm. Drug was released in a controlled manner up to 12 h. (RDC 1/6/2011)
