2/4/2011
Magnolol entrapped ultra-fine fibrous mats electrospun from poly(ethylene glycol)-b-poly(L-lactide) and in vitro release
(173-179) Chinese Journal of Polymer Science 29, #2 (2011)
Hao et al, China prepared ultra-fine fibrous mats with magnolol entrapped by electrospinning biodegradable copolymer poly(ethylene glycol) blocked poly(L-lactide).  Fibers with 10%, 20% and 30% drug entrapped respect to polymer (mass ratio) presented dramatically different drug release behavior and degradation behavior under the effect of proteinase K. The reason may be that fibers with 10% drug entrapped was more easily affected by enzyme while, to some degree, magnolol in fibers with 20% and 30% entrapped prevented polymer from being degraded by enzyme.  (RDC 2/11/2011)